A number of studies published in the last 5 years have shown that very high dose sublingual immunotherapy (SLIT), where allergen extracts (tablets, sprays or drops) are retained under the tongue for a few minutes, then swallowed, can also be effective. Ant venom immunotherapy: a double-blind, placebo-controlled, crossover trial. Information contained in this document is not intended to replace medical advice and any questions regarding a medical diagnosis or treatment should be directed to a medical practitioner.SLIT has a longer history of use in Europe than in Australia and New Zealand, where it is used more commonly than injected immunotherapy. Golden DB, Kagey-Sobotka A, Norman PS, Hamilton RG, Lichtenstein LM. Development of this document is not funded by any commercial sources and is not influenced by commercial organisations.The main disadvantage of this form of treatment is cost as more allergen needs to be swallowed than injected, resulting in the cost per allergen being more expensive than injected treatments. It is not yet clear if sublingual immunotherapy is as effective as allergy injections. Berto P, Bassi M, Incorvaia C, Frati F, Puccinelli P, Giaquinto C, Cantarutti L, Ortolani C. Common methods for taking the allergen extracts: Currently, sublingual immunotherapy is not available for insect venom immunotherapy. Specific immunotherapy for food allergy: basic principles and clinical aspects. Cost effectiveness of sublingual immunotherapy in children with allergic rhinitis and asthma. More severe reactions (such as anaphylaxis) are uncommon, however predicting who might have the serious reactions is difficult. Patients are normally advised to: It is important to inform your doctor about any reactions you may have experienced after your last injection and any new medications you are taking (such as eye drops, new heart/blood pressure tablets) or if you become pregnant. Novembre E, Galli E, Landi F, Caffarelli C, Pifferi M, De Marco E, Burastero SE, Calori G, Benetti L, Bonazza P, Puccinelli P, Parmiani S, Bernardini R, Vierucci A.
Immunotherapy injections should always be administered in a medical facility under medical supervision. It is important to note that allergen immunotherapy should only be initiated by a doctor who is fully trained in allergy.Immunotherapy has been given by injection for more than 100 years and many studies prove that it is effective. © ASCIA 2016 ASCIA is the peak professional body of clinical immunology/allergy specialists in Australia and New Zealand Website: Email: Postal address: PO Box 450 Balgowlah NSW 2093 Australia Disclaimer This document has been developed and peer reviewed by ASCIA members and is based on expert opinion and the available published literature at the time of review.Allergen immunotherapy is the closest thing we have for a "cure" for allergy, reducing the severity of symptoms and the need for medication for many allergy sufferers.
Allergen immunotherapy involves the regular administration of gradually increasing doses of allergen extracts over a period of years.
Antihistaminic, anti-inflammatory, and antiallergic properties of the non-sedating second-generation antihistamine desloratadine: a review of the evidence.